Chapman & Hall/CRC Biostatistics Series
About the Book Series
The primary objectives of the series are to provide useful reference books for researchers and scientists in academia, industry, and government, and also to offer textbooks for undergraduate and graduate courses in the areas of biostatistics and bioinformatics. The book series will provide comprehensive and unified presentations of statistical designs and analyses of important applications in biostatistics and bioinformatics, such as those in biological and biomedical research.
The scope of the series is wide, including applications of statistical methodology in biology, epidemiology, genetics, pharmaceutical science and clinical trials, public health, and medicine. The series is committed to providing easy to understand, state-of-the-art references and textbooks. In each volume, statistical concepts and methodologies will be illustrated through real world examples whenever possible.
Please contact us if you have an idea for a book for the series.
Sample Size Calculations in Clinical Research
3rd Edition
By Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina
September 30, 2020
Praise for the Second Edition:"… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics"This impressive book contains formulae for computing sample size ...
Advanced Bayesian Methods for Medical Test Accuracy
1st Edition
By Lyle D. Broemeling
June 30, 2020
Useful in many areas of medicine and biology, Bayesian methods are particularly attractive tools for the design of clinical trials and diagnostic tests, which are based on established information, usually from related previous studies. Advanced Bayesian Methods for Medical Test Accuracy begins with...
Bayesian Analysis Made Simple: An Excel GUI for WinBUGS
1st Edition
By Phil Woodward
June 30, 2020
Although the popularity of the Bayesian approach to statistics has been growing for years, many still think of it as somewhat esoteric, not focused on practical issues, or generally too difficult to understand.Bayesian Analysis Made Simple is aimed at those who wish to apply Bayesian methods but ...
Bayesian Methods for Measures of Agreement
1st Edition
By Lyle D. Broemeling
June 30, 2020
Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process.The author employs a ...
Bayesian Methods in Epidemiology
1st Edition
By Lyle D. Broemeling
June 30, 2020
Written by a biostatistics expert with over 20 years of experience in the field, Bayesian Methods in Epidemiology presents statistical methods used in epidemiology from a Bayesian viewpoint. It employs the software package WinBUGS to carry out the analyses and offers the code in the text and for ...
Benefit-Risk Assessment in Pharmaceutical Research and Development
1st Edition
Edited
By Andreas Sashegyi, James Felli, Rebecca Noel
June 30, 2020
Many practitioners in the pharmaceutical industry are still largely unfamiliar with benefit-risk assessment, despite its growing prominence in drug development and commercialization. Helping to alleviate this knowledge gap, Benefit-Risk Assessment in Pharmaceutical Research and Development provides...
Clinical Trial Methodology
1st Edition
By Karl E. Peace, Ding-Geng (Din) Chen
June 30, 2020
Now viewed as its own scientific discipline, clinical trial methodology encompasses the methods required for the protection of participants in a clinical trial and the methods necessary to provide a valid inference about the objective of the trial. Drawing from the authors’ courses on the subject ...
Confidence Intervals for Proportions and Related Measures of Effect Size
1st Edition
By Robert Gordon Newcombe
June 30, 2020
Confidence Intervals for Proportions and Related Measures of Effect Size illustrates the use of effect size measures and corresponding confidence intervals as more informative alternatives to the most basic and widely used significance tests. The book provides you with a deep understanding of what ...
Controversial Statistical Issues in Clinical Trials
1st Edition
By Shein-Chung Chow
June 30, 2020
In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good statistical practice and good clinical practice. But by identifying the causes of the issues and correcting them, the study objectives of clinical trials can be better achieved. ...
Design and Analysis of Animal Studies in Pharmaceutical Development
1st Edition
Edited
By Shein-Chung Chow, Jen-pei Liu
June 30, 2020
"Provides well-integrated, comprehensive coverage of all the major statistical designs and methods used for animal studies in pharmaceutical research and development. Demonstrates the correct way to interpret the results of animal studies in the risk assessment of biopharmaceutical products and ...
Design and Analysis of Bridging Studies
1st Edition
Edited
By Jen-pei Liu, Shein-Chung Chow, Chin-Fu Hsiao
June 30, 2020
As the development of medicines has become more globalized, the geographic variations in the efficacy and safety of pharmaceutical products need to be addressed. To accelerate the product development process and shorten approval time, researchers are beginning to design multiregional trials that ...
Design and Analysis of Non-Inferiority Trials
1st Edition
By Mark D. Rothmann, Brian L. Wiens, Ivan S.F. Chan
June 30, 2020
The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the ...