Chapman & Hall/CRC Biostatistics Series
About the Book Series
The primary objectives of the series are to provide useful reference books for researchers and scientists in academia, industry, and government, and also to offer textbooks for undergraduate and graduate courses in the areas of biostatistics and bioinformatics. The book series will provide comprehensive and unified presentations of statistical designs and analyses of important applications in biostatistics and bioinformatics, such as those in biological and biomedical research.
The scope of the series is wide, including applications of statistical methodology in biology, epidemiology, genetics, pharmaceutical science and clinical trials, public health, and medicine. The series is committed to providing easy to understand, state-of-the-art references and textbooks. In each volume, statistical concepts and methodologies will be illustrated through real world examples whenever possible.
Please contact us if you have an idea for a book for the series.
Theory of Drug Development
1st Edition
By Eric B. Holmgren
September 18, 2018
Theory of Drug Development presents a formal quantitative framework for understanding drug development that goes beyond simply describing the properties of the statistics in individual studies. It examines the drug development process from the perspectives of drug companies and regulatory agencies....
Design and Analysis of Clinical Trials with Time-to-Event Endpoints
1st Edition
Edited
By Karl E. Peace
September 10, 2018
Using time-to-event analysis methodology requires careful definition of the event, censored observation, provision of adequate follow-up, number of events, and independence or "noninformativeness" of the censoring mechanisms relative to the event. Design and Analysis of Clinical Trials with ...
Bayesian Methods for Repeated Measures
1st Edition
By Lyle D. Broemeling
June 01, 2018
Analyze Repeated Measures Studies Using Bayesian Techniques Going beyond standard non-Bayesian books, Bayesian Methods for Repeated Measures presents the main ideas for the analysis of repeated measures and associated designs from a Bayesian viewpoint. It describes many inferential methods for ...
Medical Biostatistics
4th Edition
By Abhaya Indrayan, Rajeev Kumar Malhotra
December 06, 2017
Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Fourth Edition focuses on the statistical aspects ofmedicine with a medical perspective, showing the utility of biostatistics as a tool to manage many medical uncertainties. This edition includes more topics in order to fill...
Patient-Reported Outcomes: Measurement, Implementation and Interpretation
1st Edition
By Joseph C. Cappelleri, Kelly H. Zou, Andrew G. Bushmakin, Jose Ma. J. Alvir, Demissie Alemayehu, Tara Symonds
November 16, 2016
Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for ...
Adaptive Design Theory and Implementation Using SAS and R
2nd Edition
By Mark Chang
October 14, 2016
Get Up to Speed on Many Types of Adaptive Designs Since the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second ...
Modern Adaptive Randomized Clinical Trials: Statistical and Practical Aspects
1st Edition
Edited
By Oleksandr Sverdlov
June 30, 2015
Is adaptive randomization always better than traditional fixed-schedule randomization? Which procedures should be used and under which circumstances? What special considerations are required for adaptive randomized trials? What kind of statistical inference should be used to achieve valid and ...
Biostatistics: A Computing Approach
1st Edition
By Stewart Anderson
December 20, 2011
The emergence of high-speed computing has facilitated the development of many exciting statistical and mathematical methods in the last 25 years, broadening the landscape of available tools in statistical investigations of complex data. Biostatistics: A Computing Approach focuses on visualization ...
Statistical Evaluation of Diagnostic Performance: Topics in ROC Analysis
1st Edition
By Kelly H. Zou, Aiyi Liu, Andriy I. Bandos, Lucila Ohno-Machado, Howard E. Rockette
July 27, 2011
Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents ...
Dose Finding by the Continual Reassessment Method
1st Edition
By Ying Kuen Cheung
March 29, 2011
As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to "novel" methods proposed in the past two decades. In particular, the Continual Reassessment Method (CRM) and its variations have drawn much attention in the medical ...
Group Sequential Methods with Applications to Clinical Trials
1st Edition
By Christopher Jennison, Bruce W. Turnbull
September 15, 1999
Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early...