Chapman & Hall/CRC Biostatistics Series
About the Book Series
The primary objectives of the series are to provide useful reference books for researchers and scientists in academia, industry, and government, and also to offer textbooks for undergraduate and graduate courses in the areas of biostatistics and bioinformatics. The book series will provide comprehensive and unified presentations of statistical designs and analyses of important applications in biostatistics and bioinformatics, such as those in biological and biomedical research.
The scope of the series is wide, including applications of statistical methodology in biology, epidemiology, genetics, pharmaceutical science and clinical trials, public health, and medicine. The series is committed to providing easy to understand, state-of-the-art references and textbooks. In each volume, statistical concepts and methodologies will be illustrated through real world examples whenever possible.
Please contact us if you have an idea for a book for the series.
Single-Arm Phase II Survival Trial Design
1st Edition
By Jianrong Wu
July 24, 2023
Single-Arm Phase II Survival Trial Design provides a comprehensive summary to the most commonly- used methods for single-arm phase II trial design with time-to-event endpoints. Single-arm phase II trials are a key component for successfully developing advanced cancer drugs and treatments, ...
Statistical Methods in Health Disparity Research
1st Edition
By J. Sunil Rao
July 11, 2023
A health disparity refers to a higher burden of illness, injury, disability, or mortality experienced by one group relative to others attributable to multiple factors including socioeconomic status, environmental factors, insufficient access to health care, individual risk factors, and behaviors ...
Signal Detection for Medical Scientists: Likelihood Ratio Test-based Methodology
1st Edition
By Ram Tiwari, Jyoti Zalkikar, Lan Huang
June 26, 2023
Signal Detection for Medical Scientists: Likelihood Ratio Based Test-Based Methodology presents the data mining techniques with focus on likelihood ratio test (LRT) based methods for signal detection. It emphasizes computational aspect of LRT methodology and is pertinent for first-time researchers ...
Controlled Epidemiological Studies
1st Edition
By Marie Reilly
May 26, 2023
This book covers classic epidemiological designs that use a reference/control group, including case-control, case-cohort, nested case-control and variations of these designs, such as stratified and two-stage designs. It presents a unified view of these sampling designs as representations of an ...
ROC Analysis for Classification and Prediction in Practice
1st Edition
By Christos Nakas, Leonidas Bantis, Constantine Gatsonis
May 26, 2023
This book presents a unified and up-to-date introduction to ROC methodologies, covering both diagnosis (classification) and prediction. The emphasis is on the conceptual underpinning of ROC analysis and the practical implementation in diverse scientific fields. A plethora of examples accompany the ...
Design and Analysis of Pragmatic Trials
1st Edition
By Song Zhang, Chul Ahn, Hong Zhu
May 16, 2023
This book begins with an introduction of pragmatic cluster randomized trials (PCTs) and reviews various pragmatic issues that need to be addressed by statisticians at the design stage. It discusses the advantages and disadvantages of each type of PCT, and provides sample size formulas, sensitivity ...
Statistical Analytics for Health Data Science with SAS and R
1st Edition
By Jeffrey Wilson, Ding-Geng Chen, Karl E. Peace
March 28, 2023
This book aims to compile typical fundamental-to-advanced statistical methods to be used for health data sciences. Although the book promotes applications to health and health-related data, the models in the book can be used to analyze any kind of data. The data are analyzed with the commonly used ...
Drug Development for Rare Diseases
1st Edition
Edited
By Bo Yang, Yang Song, Yijie Zhou
February 13, 2023
A disease is defined as rare if the prevalence is fewer than 200,000 in the United States. It is estimated that there are more than 7,000 rare diseases, which collectively affect 30 million Americans or 10% of the US population. This diverse and complex disease area poses challenges for patients, ...
Adaptive Design Methods in Clinical Trials
2nd Edition
By Shein-Chung Chow, Mark Chang
January 21, 2023
With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA’s recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and ...
Bayesian Methods in Health Economics
1st Edition
By Gianluca Baio
January 21, 2023
Health economics is concerned with the study of the cost-effectiveness of health care interventions. This book provides an overview of Bayesian methods for the analysis of health economic data. After an introduction to the basic economic concepts and methods of evaluation, it presents Bayesian ...
Design and Analysis of Bioavailability and Bioequivalence Studies
3rd Edition
By Shein-Chung Chow, Jen-pei Liu
January 21, 2023
Preeminent Experts Update a Well-Respected BookTaking into account the regulatory and scientific developments that have occurred since the second edition, Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition provides a complete presentation of the latest progress of ...
Handbook of Regression and Modeling: Applications for the Clinical and Pharmaceutical Industries
1st Edition
By Daryl S. Paulson
January 21, 2023
Carefully designed for use by clinical and pharmaceutical researchers and scientists, Handbook of Regression Analysis and Modeling explores statistical methods that have been adapted into biological applications for the quickly evolving field of biostatistics. The author clearly delineates a ...