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Chapman & Hall/CRC Biostatistics Series

About the Book Series

The primary objectives of the series are to provide useful reference books for researchers and scientists in academia, industry, and government, and also to offer textbooks for undergraduate and graduate courses in the areas of biostatistics and bioinformatics. The book series will provide comprehensive and unified presentations of statistical designs and analyses of important applications in biostatistics and bioinformatics, such as those in biological and biomedical research.

The scope of the series is wide, including applications of statistical methodology in biology, epidemiology, genetics, pharmaceutical science and clinical trials, public health, and medicine. The series is committed to providing easy to understand, state-of-the-art references and textbooks. In each volume, statistical concepts and methodologies will be illustrated through real world examples whenever possible.

Please contact us if you have an idea for a book for the series.

75 Series Titles


Statistical Evaluation of Diagnostic Performance Topics in ROC Analysis

Statistical Evaluation of Diagnostic Performance: Topics in ROC Analysis

1st Edition

By Kelly H. Zou, Aiyi Liu, Andriy I. Bandos, Lucila Ohno-Machado, Howard E. Rockette
July 27, 2011

Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents ...

Dose Finding by the Continual Reassessment Method

Dose Finding by the Continual Reassessment Method

1st Edition

By Ying Kuen Cheung
March 29, 2011

As clinicians begin to realize the important role of dose-finding in the drug development process, there is an increasing openness to "novel" methods proposed in the past two decades. In particular, the Continual Reassessment Method (CRM) and its variations have drawn much attention in the medical ...

Group Sequential Methods with Applications to Clinical Trials

Group Sequential Methods with Applications to Clinical Trials

1st Edition

By Christopher Jennison, Bruce W. Turnbull
September 15, 1999

Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early...

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