Chapman & Hall/CRC Biostatistics Series
About the Book Series
The primary objectives of the series are to provide useful reference books for researchers and scientists in academia, industry, and government, and also to offer textbooks for undergraduate and graduate courses in the areas of biostatistics and bioinformatics. The book series will provide comprehensive and unified presentations of statistical designs and analyses of important applications in biostatistics and bioinformatics, such as those in biological and biomedical research.
The scope of the series is wide, including applications of statistical methodology in biology, epidemiology, genetics, pharmaceutical science and clinical trials, public health, and medicine. The series is committed to providing easy to understand, state-of-the-art references and textbooks. In each volume, statistical concepts and methodologies will be illustrated through real world examples whenever possible.
Please contact us if you have an idea for a book for the series.
Bayesian Methods in Pharmaceutical Research
1st Edition
Edited
By Emmanuel Lesaffre, Gianluca Baio, Bruno Boulanger
December 13, 2021
Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian ...
Biomarker Analysis in Clinical Trials with R
1st Edition
By Nusrat Rabbee
December 13, 2021
The world is awash in data. This volume of data will continue to increase. In the pharmaceutical industry, much of this data explosion has happened around biomarker data. Great statisticians are needed to derive understanding from these data. This book will guide you as you begin the journey into ...
Estimands, Estimators and Sensitivity Analysis in Clinical Trials
1st Edition
By Craig Mallinckrodt, Geert Molenberghs, Ilya Lipkovich, Bohdana Ratitch
December 13, 2021
The concepts of estimands, analyses (estimators), and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts as a practical guide to developing and implementing statistical analysis plans by explaining fundamental concepts using ...
Statistical Methods for Healthcare Performance Monitoring
1st Edition
By Alex Bottle, Paul Aylin
December 13, 2021
Healthcare is important to everyone, yet large variations in its quality have been well documented both between and within many countries. With demand and expenditure rising, it’s more crucial than ever to know how well the healthcare system and all its components – from staff member to regional ...
Statistical Design, Monitoring, and Analysis of Clinical Trials: Principles and Methods
2nd Edition
By Weichung Joe Shih, Joseph Aisner
October 26, 2021
Statistical Design, Monitoring, and Analysis of Clinical Trials, Second Edition concentrates on the biostatistics component of clinical trials. This new edition is updated throughout and includes five new chapters. Developed from the authors’ courses taught to public health and medical students, ...
Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies
1st Edition
By Harry Yang, Steven Novick
September 30, 2021
Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian ...
Bayesian Applications in Pharmaceutical Development
1st Edition
Edited
By Mani Lakshminarayanan, Fanni Natanegara
September 30, 2021
The cost for bringing new medicine from discovery to market has nearly doubled in the last decade and has now reached $2.6 billion. There is an urgent need to make drug development less time-consuming and less costly. Innovative trial designs/ analyses such as the Bayesian approach are essential to...
Innovative Statistics in Regulatory Science
1st Edition
By Shein-Chung Chow
June 30, 2021
Statistical methods that are commonly used in the review and approval process of regulatory submissions are usually referred to as statistics in regulatory science or regulatory statistics. In a broader sense, statistics in regulatory science can be defined as valid statistics that are employed in ...
Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials
1st Edition
By Mark Chang, John Balser, Jim Roach, Robin Bliss
June 30, 2021
"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development…. Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these ...
Self-Controlled Case Series Studies: A Modelling Guide with R
1st Edition
By Paddy Farrington, Heather Whitaker, Yonas Ghebremichael Weldeselassie
June 30, 2021
Self-Controlled Case Series Studies: A Modelling Guide with R provides the first comprehensive account of the self-controlled case series (SCCS) method, a statistical technique for investigating associations between outcome events and time-varying exposures. The method only requires information ...
Statistical Topics in Health Economics and Outcomes Research
1st Edition
Edited
By Demissie Alemayehu, Joseph C. Cappelleri, Birol Emir, Kelly H. Zou
June 30, 2021
With ever-rising healthcare costs, evidence generation through Health Economics and Outcomes Research (HEOR) plays an increasingly important role in decision-making about the allocation of resources. Accordingly, it is now customary for health technology assessment and reimbursement agencies to ...
Bioequivalence and Statistics in Clinical Pharmacology
2nd Edition
By Scott D. Patterson, Byron Jones
March 31, 2021
Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and ...