Chapman & Hall/CRC Biostatistics Series
About the Book Series
The primary objectives of the series are to provide useful reference books for researchers and scientists in academia, industry, and government, and also to offer textbooks for undergraduate and graduate courses in the areas of biostatistics and bioinformatics. The book series will provide comprehensive and unified presentations of statistical designs and analyses of important applications in biostatistics and bioinformatics, such as those in biological and biomedical research.
The scope of the series is wide, including applications of statistical methodology in biology, epidemiology, genetics, pharmaceutical science and clinical trials, public health, and medicine. The series is committed to providing easy to understand, state-of-the-art references and textbooks. In each volume, statistical concepts and methodologies will be illustrated through real world examples whenever possible.
Please contact us if you have an idea for a book for the series.
Dynamical Biostatistical Models
1st Edition
By Daniel Commenges, Helene Jacqmin-Gadda
December 18, 2020
Dynamical Biostatistical Models presents statistical models and methods for the analysis of longitudinal data. The book focuses on models for analyzing repeated measures of quantitative and qualitative variables and events history, including survival and multistate models. Most of the advanced ...
Emerging Non-Clinical Biostatistics in Biopharmaceutical Development and Manufacturing
1st Edition
By Harry Yang
December 18, 2020
The premise of Quality by Design (QbD) is that the quality of the pharmaceutical product should be based upon a thorough understanding of both the product and the manufacturing process. This state-of-the-art book provides a single source of information on emerging statistical approaches to QbD and ...
Exposure-Response Modeling: Methods and Practical Implementation
1st Edition
By Jixian Wang
December 18, 2020
Discover the Latest Statistical Approaches for Modeling Exposure-Response RelationshipsWritten by an applied statistician with extensive practical experience in drug development, Exposure-Response Modeling: Methods and Practical Implementation explores a wide range of topics in exposure-response ...
Methods in Comparative Effectiveness Research
1st Edition
Edited
By Constantine Gatsonis, Sally C. Morton
December 18, 2020
Comparative effectiveness research (CER) is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care (IOM 2009). CER is conducted to develop evidence that ...
Mixture Modelling for Medical and Health Sciences
1st Edition
By Shu Kay Ng, Liming Xiang, Kelvin Kai Wing Yau
December 18, 2020
Mixture Modelling for Medical and Health Sciences provides a direct connection between theoretical developments in mixture modelling and their applications in real world problems. The book describes the development of the most important concepts through comprehensive analyses of real and practical ...
Multiregional Clinical Trials for Simultaneous Global New Drug Development
1st Edition
Edited
By Joshua Chen, Hui Quan
December 18, 2020
In a global clinical development strategy, multiregional clinical trials (MRCTs) are vital in the development of innovative medicines. Multiregional Clinical Trials for Simultaneous Global New Drug Development presents a comprehensive overview on the current status of conducting MRCTs in clinical ...
Platform Trial Designs in Drug Development: Umbrella Trials and Basket Trials
1st Edition
Edited
By Zoran Antonijevic, Robert A. Beckman
December 18, 2020
Platform trials test multiple therapies in one indication, one therapy for multiple indications, or both. These novel clinical trial designs can dramatically increase the cost-effectiveness of drug development, leading to life-altering medicines for people suffering from serious illnesses, possibly...
Randomization, Masking, and Allocation Concealment
1st Edition
Edited
By Vance Berger
December 18, 2020
Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly.Far too often the subtle nuances that distinguish proper randomization from flawed ...
Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials
1st Edition
By Toshiro Tango
December 18, 2020
Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The ...
Statistical Methods for Immunogenicity Assessment
1st Edition
By Harry Yang, Jianchun Zhang, Binbing Yu, Wei Zhao
December 18, 2020
Develop Effective Immunogenicity Risk Mitigation StrategiesImmunogenicity assessment is a prerequisite for the successful development of biopharmaceuticals, including safety and efficacy evaluation. Using advanced statistical methods in the study design and analysis stages is therefore essential to...
Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R
1st Edition
By Jianrong Wu
December 18, 2020
Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint. Traditional cancer trial designs with ...
Statistical Methods in Drug Combination Studies
1st Edition
Edited
By Wei Zhao, Harry Yang
December 18, 2020
The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it possible to apply these emerging statistical methods in in ...